Pneumococcal conjugate vaccine (PCV) schedules for the Northern Territory (NT): randomised controlled trial of booster vaccines to broaden and strengthen protection from invasive and mucosal infections.
Pneumococcal conjugate vaccine (PCV) schedules for the Northern Territory (NT): randomised controlled trial of booster vaccines to broaden and strengthen protection from invasive and mucosal infections.
批准号:
nhmrc : 1046999
负责人:
A/Pr Heidi Smith-Vaughan
金额:
$138.62万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2017-12-31
中文摘要
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英文摘要
Very few Indigenous children in remote communities have healthy ears or lungs; almost 20% have eardrum perforations. The associated hearing loss causes educational disadvantage with life long impacts on quality of life. New pneumococcal conjugate vaccines target a broader diversity of pathogens that cause eardrum perforation and lung infections, but the best schedules and combinations have not been tested. This randomised controlled trial will compare immune response, bacterial carriage and clinical outcomes of different vaccine schedules.
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会议论文
Preventing early-onset pneumonia in Indigenous infants through maternal immunisation: a multi-centre randomised controlled trial
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批准号:nhmrc : 1138555
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项目类别:Project Grants
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资助金额:$217.08万
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财政年份:2018
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
Understanding the role of the two major bacterial pathogens in the upper and lower airways of Indigenous children with chronic lung disease
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批准号:nhmrc : GNT1100310
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项目类别:Project Grants
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资助金额:$74.33万
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财政年份:2016
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
Understanding the role of the two major bacterial pathogens in the upper and lower airways of Indigenous children with chronic lung disease
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批准号:nhmrc : 1100310
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项目类别:Project Grants
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资助金额:$51.05万
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财政年份:2016
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
Molecular public health in Australian Indigenous communities and developing countries in our region to improve ear and respiratory outcomes
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批准号:nhmrc : 1024175
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项目类别:Career Development Fellowships
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资助金额:$27.23万
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财政年份:2012
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
A multi-centre, double-blind, randomised controlled trial to evaluate the efficacy of 10 valent-pneumococcal-Protein D conjugate vaccine in reducing respiratory exacerbations in children aged ? 18 months with suppurative lung disease
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批准号:nhmrc : 1019904
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项目类别:Project Grants
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资助金额:$77.39万
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财政年份:2012
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
Identifying the microbiological risk factors for acute lower respiratory infection in Indigenous children to inform future intervention strategies
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批准号:nhmrc : 1023781
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项目类别:Project Grants
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资助金额:$33.06万
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财政年份:2012
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
Single versus combination pneumococcal conjugate vaccines (13PCV and PHiD-CV) for high-risk Aboriginal children (COMBO)
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批准号:nhmrc : 605810
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项目类别:NHMRC Project Grants
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资助金额:$201.2万
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财政年份:2010
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
Community-based surveillance of bacterial respiratory pathogens in the NT and WA
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批准号:nhmrc : 545232
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项目类别:NHMRC Project Grants
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资助金额:$52.2万
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财政年份:2009
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
Do respiratory viruses explain high rates of acute otitis media with perforation in young Aboriginal children
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批准号:nhmrc : 490317
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项目类别:NHMRC Project Grants
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资助金额:$13.81万
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财政年份:2008
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
Azithromycin versus placebo in the treatment of asymptomatic acute otitis media in young Aboriginal children : A RCT
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批准号:nhmrc : 436023
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项目类别:NHMRC Project Grants
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资助金额:$90.52万
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财政年份:2007
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
Applying Molecular Public Health in Indigenous Communities: Linking research to outcomes
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批准号:nhmrc : 283327
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项目类别:Early Career Fellowships
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资助金额:$10.11万
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财政年份:2004
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
Pneumococcal surveillance in the Northern Territory: implications of vaccination and mass treatment programs
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批准号:nhmrc : 236218
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项目类别:NHMRC Project Grants
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资助金额:$35.95万
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财政年份:2003
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
Implications of bacterial load for vaccine efficacy and antibiotic treatment outcomes in high-risk populations
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批准号:nhmrc : 236211
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项目类别:NHMRC Project Grants
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资助金额:$23.0万
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财政年份:2003
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
Judicious use of antibiotics for acute otitis media in Aboriginal children: A multi-centre clinical trial
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批准号:nhmrc : 193306
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项目类别:NHMRC Project Grants
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资助金额:$41.0万
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财政年份:2002
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负责人:A/Pr Heidi Smith-Vaughan
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依托单位:
海外基金