A multi-centre, double-blind, randomised controlled trial to evaluate the efficacy of 10 valent-pneumococcal-Protein D conjugate vaccine in reducing respiratory exacerbations in children aged ? 18 months with suppurative lung disease
一项多中心、双盲、随机对照试验,旨在评估 10 价肺炎球菌-蛋白 D 结合疫苗在减少 4 岁儿童呼吸道症状加重方面的功效。
基本信息
- 批准号:nhmrc : 1019904
- 负责人:
- 金额:$ 77.39万
- 依托单位:
- 依托单位国家:澳大利亚
- 项目类别:Project Grants
- 财政年份:2012
- 资助国家:澳大利亚
- 起止时间:2012-01-01 至 2016-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Chronic suppurative (ie infected) lung diseases in children are major causes of poor health and deaths worldwide. Repeated childhood infections contribute to poor lung health in adults. The most common organism causing infection is non-typeable Haemophilus influenzae (NTHi). This study aims to determine whether a vaccine against NTHi can reduce repeated respiratory infections in children. If so, vaccination may lead to substantial improvements in current/ future lung health, and considerable direct and indirect cost of disease savings.
儿童慢性化脓性肺病是世界范围内健康状况不佳和死亡的主要原因。儿童期反复感染会导致成人肺部健康状况不佳。最常见的引起感染的微生物是不可分型的流感嗜血杆菌(NTHi)。这项研究旨在确定NTHi疫苗是否可以减少儿童反复呼吸道感染。如果是这样的话,疫苗接种可能会导致当前/未来肺部健康的大幅改善,并节省相当多的直接和间接疾病成本。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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A/Pr Heidi Smith-Vaughan其他文献
A/Pr Heidi Smith-Vaughan的其他文献
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{{ truncateString('A/Pr Heidi Smith-Vaughan', 18)}}的其他基金
Preventing early-onset pneumonia in Indigenous infants through maternal immunisation: a multi-centre randomised controlled trial
通过母亲免疫预防土著婴儿早发性肺炎:一项多中心随机对照试验
- 批准号:
nhmrc : 1138555 - 财政年份:2018
- 资助金额:
$ 77.39万 - 项目类别:
Project Grants
Understanding the role of the two major bacterial pathogens in the upper and lower airways of Indigenous children with chronic lung disease
了解两种主要细菌病原体在患有慢性肺病的土著儿童上呼吸道和下呼吸道中的作用
- 批准号:
nhmrc : GNT1100310 - 财政年份:2016
- 资助金额:
$ 77.39万 - 项目类别:
Project Grants
Understanding the role of the two major bacterial pathogens in the upper and lower airways of Indigenous children with chronic lung disease
了解两种主要细菌病原体在患有慢性肺病的土著儿童上呼吸道和下呼吸道中的作用
- 批准号:
nhmrc : 1100310 - 财政年份:2016
- 资助金额:
$ 77.39万 - 项目类别:
Project Grants
Pneumococcal conjugate vaccine (PCV) schedules for the Northern Territory (NT): randomised controlled trial of booster vaccines to broaden and strengthen protection from invasive and mucosal infections.
北领地 (NT) 肺炎球菌结合疫苗 (PCV) 时间表:加强疫苗的随机对照试验,以扩大和加强对侵袭性和粘膜感染的保护。
- 批准号:
nhmrc : 1046999 - 财政年份:2013
- 资助金额:
$ 77.39万 - 项目类别:
Project Grants
Molecular public health in Australian Indigenous communities and developing countries in our region to improve ear and respiratory outcomes
澳大利亚土著社区和本地区发展中国家的分子公共卫生,以改善耳朵和呼吸系统的结果
- 批准号:
nhmrc : 1024175 - 财政年份:2012
- 资助金额:
$ 77.39万 - 项目类别:
Career Development Fellowships
Identifying the microbiological risk factors for acute lower respiratory infection in Indigenous children to inform future intervention strategies
确定土著儿童急性下呼吸道感染的微生物危险因素,为未来的干预策略提供信息
- 批准号:
nhmrc : 1023781 - 财政年份:2012
- 资助金额:
$ 77.39万 - 项目类别:
Project Grants
Single versus combination pneumococcal conjugate vaccines (13PCV and PHiD-CV) for high-risk Aboriginal children (COMBO)
针对高危原住民儿童的单一肺炎球菌结合疫苗(13PCV 和 PHiD-CV)与联合疫苗(COMBO)
- 批准号:
nhmrc : 605810 - 财政年份:2010
- 资助金额:
$ 77.39万 - 项目类别:
NHMRC Project Grants
Community-based surveillance of bacterial respiratory pathogens in the NT and WA
北领地和西澳细菌呼吸道病原体的社区监测
- 批准号:
nhmrc : 545232 - 财政年份:2009
- 资助金额:
$ 77.39万 - 项目类别:
NHMRC Project Grants
Do respiratory viruses explain high rates of acute otitis media with perforation in young Aboriginal children
呼吸道病毒是否可以解释原住民儿童急性中耳炎穿孔的高发病率
- 批准号:
nhmrc : 490317 - 财政年份:2008
- 资助金额:
$ 77.39万 - 项目类别:
NHMRC Project Grants
Azithromycin versus placebo in the treatment of asymptomatic acute otitis media in young Aboriginal children : A RCT
阿奇霉素与安慰剂治疗年轻原住民儿童无症状急性中耳炎:一项随机对照试验
- 批准号:
nhmrc : 436023 - 财政年份:2007
- 资助金额:
$ 77.39万 - 项目类别:
NHMRC Project Grants
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