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A multi-centre, double-blind, randomised controlled trial to evaluate the efficacy of 10 valent-pneumococcal-Protein D conjugate vaccine in reducing respiratory exacerbations in children aged ? 18 months with suppurative lung disease

A multi-centre, double-blind, randomised controlled trial to evaluate the efficacy of 10 valent-pneumococcal-Protein D conjugate vaccine in reducing respiratory exacerbations in children aged ? 18 months with suppurative lung disease
一项多中心、双盲、随机对照试验，旨在评估 10 价肺炎球菌-蛋白 D 结合疫苗在减少 4 岁儿童呼吸道症状加重方面的功效。
批准号：
nhmrc : 1019904
负责人：
A/Pr Heidi Smith-Vaughan
金额：
$77.39万
依托单位：
Queensland University of Technology
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2012
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2012-01-01 至 2016-12-31
来源：
https://researchdata.edu.au/multi-centre-double-lung-disease/109989
关键词：
multicentredoubleblindrandomised

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中文摘要
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英文摘要
Chronic suppurative (ie infected) lung diseases in children are major causes of poor health and deaths worldwide. Repeated childhood infections contribute to poor lung health in adults. The most common organism causing infection is non-typeable Haemophilus influenzae (NTHi). This study aims to determine whether a vaccine against NTHi can reduce repeated respiratory infections in children. If so, vaccination may lead to substantial improvements in current/ future lung health, and considerable direct and indirect cost of disease savings.
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