Post-transcriptional gene regulation in RNA-granules

RNA颗粒中的转录后基因调控

• 批准号: nhmrc : 606575
• 负责人: Dr Peter Boag
• 金额: $ 35.56万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/post-transcriptional-gene-rna-granules/76998
• 关键词: Post; transcriptional; gene; regulation; RNA

This project is focused on understanding pathways that regulate RNA metabolism and development. Using the powerful C. elegans model organism (nonpathogenic roundworm) we will undertake experiments to identify pathways that regulate how some mRNAs are stored and later activated during reproduction. The outcomes of these experiments should provide many interesting clues as to how development is regulated by posttranscriptional mechanisms, and have broad relevance to other tissues and organisms.

该项目的重点是了解调节RNA代谢和发育的途径。使用强大的C。我们将进行实验，以确定调节某些mRNA如何储存并随后在生殖过程中激活的途径。这些实验的结果应该提供了许多有趣的线索，如何发展是由转录后机制的调控，并有广泛的相关性，以其他组织和生物体。