Postprandial Lipid Metabolism in Familial Hypercholersterolaemia: Mechanisms and Effects of Omega-3 Fatty Acid Ethyl Esters

家族性高胆固醇血症（FH）是已知导致过早冠心病（CHD）最常见的遗传疾病。FH增加冠心病风险的部分原因可能是由于血液中脂肪的积累。补充鱼油可能是一个新的目标，除了标准的最佳治疗，以降低冠心病风险的FH。我们的研究结果将为FH脂质紊乱的科学背后和临床治疗增加价值，并将确立鱼油的关键作用。

Familial hypercholesterolaemia (FH) is the most common genetic condition known to cause premature coronary heart diseaseis (CHD). The increasd CHD risk in FH may be in part due to accumulation of fat in blood. Fish oil supplementation may be a new target, additional to standard best therapy, for reducing CHD risk in FH. Our results will add value to the science behind and clinical therapy for lipid disorders in FH, and will establish a key role for fish oils.