Prediction of adverse outcomes following a fragility fracture

脆性骨折后不良后果的预测

• 批准号: nhmrc : 1031494
• 负责人: Dr Dana Bliuc
• 金额: $ 9.9万
• 依托单位: Garvan Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/prediction-adverse-outcomes-fragility-fracture/110809
• 关键词: Prediction; adverse; outcomes; following; fragility

Individuals with an existing fracture are at increased risk of adverse outcomes such as re-fracture and premature mortality, but it is not clear why. We propose to evaluate risk factors, and prognostic models, for predicting the risk of adverse outcomes. We also propose to develop a quantitative risk-benefit framework for evaluating the clinical utility of such prognostic models and help ensure that therapies appropriately address real-life experience of osteoporotic patients.

存在骨折的个体发生不良结局的风险增加，如再骨折和过早死亡，但原因尚不清楚。我们建议评估风险因素和预后模型，以预测不良结局的风险。我们还建议开发一个定量的风险-效益框架，用于评估此类预后模型的临床实用性，并帮助确保治疗适当地解决实际生活中的经验，患者。