Promoting regrowth of nerve fibres into the epidermis during diabetic neuropathy by LRP agonists
Promoting regrowth of nerve fibres into the epidermis during diabetic neuropathy by LRP agonists
批准号:
nhmrc : 1088952
负责人:
A/Pr Lisa Foa
金额:
$28.48万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2018-12-31
中文摘要
神经损伤可以在受伤或疾病后发展,通常非常虚弱,愈合缓慢,可能导致疼痛增加。我们的工作旨在研究一类新的分子,我们展示了这种分子可以激活神经细胞上选定的脂肪受体,以指导再生神经的生长。我们将确定这些受体是如何发挥作用的,目的是开发一种新的治疗方法,旨在修复神经损伤。
英文摘要
Nerve damage can develop post injury or disease and is often very debilitating, slow to heal and can cause increased pain. Our work aims to examine a new class of molecules that we show can activate selected fat-receptors on nerve cells to guide the growth of regenerating nerves. We will determine how these receptors function with the aim of developing a novel class of therapeutics directed at healing nerve damage.
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会议论文
Neuron to glia signalling: learning how synaptic signalling can promote CNS remyelination
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批准号:nhmrc : 1066025
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项目类别:Project Grants
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资助金额:$40.65万
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财政年份:2014
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负责人:A/Pr Lisa Foa
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依托单位:
Deciphering the mechanisms underlying LRP-mediated axon guidance
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批准号:nhmrc : 1068317
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项目类别:Project Grants
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资助金额:$24.72万
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财政年份:2014
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负责人:A/Pr Lisa Foa
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依托单位:
Transient receptor potential channels, calcium and Alzheimer's disease
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批准号:nhmrc : 1042566
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项目类别:Project Grants
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资助金额:$27.36万
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财政年份:2013
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负责人:A/Pr Lisa Foa
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依托单位:
The role of store-operated calcium entry in neuronal development
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批准号:nhmrc : 1024145
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项目类别:Project Grants
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资助金额:$23.55万
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财政年份:2012
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负责人:A/Pr Lisa Foa
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依托单位:
Post Synaptic Density Scaffold proteins in the growth cone: Homer and Shank, crucial for calcium signaling.
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批准号:nhmrc : 512801
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项目类别:NHMRC Project Grants
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资助金额:$15.86万
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财政年份:2008
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负责人:A/Pr Lisa Foa
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依托单位:
海外基金