The role of store-operated calcium entry in neuronal development

钙池操纵的钙进入在神经元发育中的作用

• 批准号: nhmrc : 1024145
• 负责人: A/Pr Lisa Foa
• 金额: $ 23.55万
• 依托单位: Antarctic Climate and Ecosystems CRC, University of Tasmania
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-store-operated-neuronal-development/110322
• 关键词: role; store; operated; calcium; entry

Defects in brain development can manifest in a range of disorders including autism and mental retardation. The highly complex, precise network that is our nervous system forms during development. Our work will determine the role of key proteins in guiding developing neurons. Understanding the function of such proteins will improve our ability to predict the outcome caused by mutations in these proteins, in the developing foetus.

大脑发育的缺陷可以表现为一系列疾病，包括自闭症和智力迟钝。我们的神经系统是在发育过程中形成的高度复杂、精确的网络。我们的工作将确定关键蛋白质在指导神经元发育中的作用。了解此类蛋白质的功能将提高我们预测这些蛋白质突变在发育中的胎儿中引起的结果的能力。