Proof-of-concept studies for a novel anti-thrombotic agent

新型抗血栓药物的概念验证研究

• 批准号: nhmrc : 1137508
• 负责人: A/Pr Justin Hamilton
• 金额: $ 42.76万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Development Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/proof-of-concept-thrombotic-agent/1318582
• 关键词: Proof; concept; studies; novel; anti

Blood clots cause most heart attacks and strokes, and platelets are the blood cells that form these clots. Drugs that block platelet function, such as aspirin, are used to prevent heart attack and stroke but are frequently ineffective. Here, we will develop a new drug that prevents platelet incorporation into blood clots, that will be suitable for the prevention of heart attack and stroke in humans, and that may improve on existing therapies.

血液凝块导致大多数心脏病发作和中风，而血小板是形成这些凝块的血细胞。阻断血小板功能的药物，如阿司匹林，用于预防心脏病发作和中风，但通常无效。在这里，我们将开发一种新的药物，防止血小板掺入血凝块，这将适用于预防心脏病发作和中风的人类，并可能改善现有的治疗。