Investigation of the role of Type II PI 3-kinases in platelet function

II 型 PI 3-激酶在血小板功能中的作用研究

• 批准号: nhmrc : 1010848
• 负责人: A/Pr Justin Hamilton
• 金额: $ 29.67万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigation-role-type-platelet-function/109532
• 关键词: Investigation; role; Type; II; PI

Inappropriate blood clot formation is the cause of most heart attacks and strokes, and platelets are the blood cells which form these clots. Current therapies that interfere with platelet function are used to prevent heart attack and stroke but are frequently ineffective. We will study the signals which control platelet incorporation into clots in order to discover improved therapeutic strategies for heart attack and stroke prevention.

不适当的血凝块形成是大多数心脏病发作和中风的原因，血小板是形成这些凝块的血细胞。目前干扰血小板功能的疗法用于预防心脏病发作和中风，但通常无效。我们将研究控制血小板与凝块结合的信号，以发现心脏病发作和中风预防的改进治疗策略。