An Integrated Genomic and Epigenomic Approach to Dissect the Aetiology of Motor Neuron Disease

点击翻译按钮获取中文摘要

Motor neuron disease (MND) is a neurological disease that destroys motor neurons, which control muscle activity, such as walking. It affects people >40 years old and most patients die within 3 years. There is no specific test for its diagnosis and there are no cures. I aim to build an independent research group to discover novel genes and epigenetic marks, and to dissect their biological function in MND. This knowledge is crucial for finding effective diagnosis, treatment and cure for MND.