Randomised controlled trial of the use of nitazoxanide versus placebo to treat gastroenteritis among Aboriginal children

使用硝唑尼特与安慰剂治疗原住民儿童胃肠炎的随机对照试验

• 批准号: nhmrc : 1069772
• 负责人: A/Pr Mark Chatfield
• 金额: $ 88.34万
• 依托单位: Curtin University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/randomised-controlled-trial-aboriginal-children/455409
• 关键词: Randomised; controlled; trial; use; nitazoxanide

Better treatment strategies are needed for Indigenous children with gastroenteritis. At present, most treatment is supportive only, with little effect on the duration of symptoms. Nitazoxanide appears to have effects on a broad range of pathogens which cause gastroenteritis, but it is not clear whether it will be of benefit in this population. We will compare the speed of symptom resolution in children who receive nitazoxanide with a group who receive a placebo instead.

需要为患有胃肠炎的土著儿童制定更好的治疗策略。目前，大多数治疗只是支持性的，对症状的持续时间影响不大。硝唑尼特似乎对引起胃肠炎的广泛病原体有影响，但尚不清楚它是否对这一人群有益。我们将比较接受硝唑尼特和接受安慰剂的儿童症状消退的速度。