Randomised controlled trial of azithromycin to reduce the morbidity of severe bronchiolitis in Indigenous infants

急性下呼吸道感染是从偏远社区住院和取回的最常见原因。早期严重的呼吸道感染可能会损害肺部生长。我们将研究是否应该使用阿奇霉素(具有抗炎特性的抗生素)来治疗毛细支气管炎住院的婴儿，以减轻毛细支气管炎的严重程度，防止再次住院。这项研究潜在地改善了急性临床护理，并预防了未来的呼吸道疾病。

Acute lower respiratory infections are the commonest cause of hospitalisations and retrievals from remote communities. Early severe respiratory infections likely impair lung growth. We will examine whether azithromycin (antibiotic with anti-inflammatory properties) should be used to treat infants hospitalised with bronchiolitis to reduce the severity of bronchiolitis and prevent rehospitalisation. The study potentially improves acute clinical care as well as prevents future respiratory illness.