Randomised controlled trial of azithromycin to reduce the morbidity of severe bronchiolitis in Indigenous infants

急性下呼吸道感染是导致住院和从偏远社区就诊的最常见原因。早期严重的呼吸道感染可能会损害肺部的生长。我们将研究是否应该使用阿奇霉素（具有抗炎特性的抗生素）治疗因毛细支气管炎住院的婴儿，以降低毛细支气管炎的严重程度并防止再次住院。这项研究有可能改善急性临床护理，并预防未来的呼吸系统疾病。

Acute lower respiratory infections are the commonest cause of hospitalisations and retrievals from remote communities. Early severe respiratory infections likely impair lung growth. We will examine whether azithromycin (antibiotic with anti-inflammatory properties) should be used to treat infants hospitalised with bronchiolitis to reduce the severity of bronchiolitis and prevent rehospitalisation. The study potentially improves acute clinical care as well as prevents future respiratory illness.