Randomised controlled trial of mixed whole-cell/acellular pertussis vaccination versus acellular-only vaccination of infants

越来越多的澳大利亚儿童患上了食物过敏，特别是自20世纪90年代末以来。为了理解原因，我们观察了当时还发生了什么变化。其中一件事是百日咳疫苗。旧疫苗被一种新疫苗取代了。儿童在幼年时会接种几剂百日咳疫苗。我们相信，接种一剂旧疫苗的儿童将不太可能患上食物过敏。我们想通过比较两组儿童来检验这一点。

More Australian children are developing food allergies, particularly since the late 1990s. To understand why, we looked at what else changed at that time. One thing was the whooping cough vaccine. The old vaccine was replaced by a new one. Children are given several doses of whooping cough vaccines when they are young. We believe children who receive one dose of the old vaccine will be less likely to develop food allergies. We want to test this by comparing two groups of children.