Analysis of killer T cell geometry during an anti-tumour response

抗肿瘤反应过程中杀伤性 T 细胞几何结构的分析

• 批准号: nhmrc : 1032670
• 负责人: Dr Paulus Mrass
• 金额: $ 36.49万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/analysis-killer-t-tumour-response/110863
• 关键词: Analysis; killer; cell; geometry; during

Cancer is a major health problem around the world. Currently used treatment options of cancer have the drawback that they also damage healthy tissues. This limits the dosages that can be administered, frequently resulting in treatment failure. Anti-tumour killer T cells are a naturally occurring cell type that can cause tumour regression. In the present proposal, we explore how the efficiency of these cell-types can be further enhanced to induce rejection of progressing tumours.

癌症是世界各地的主要健康问题。目前使用的癌症治疗选择具有它们也损害健康组织的缺点。这限制了可以施用的剂量，经常导致治疗失败。抗肿瘤杀伤T细胞是一种天然存在的细胞类型，可导致肿瘤消退。在本提案中，我们探索了如何进一步提高这些细胞类型的效率，以诱导对进展性肿瘤的排斥反应。