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The axis of Bcl-2, plasmacytoid DCs and lupus as a basis for therapy

The axis of Bcl-2, plasmacytoid DCs and lupus as a basis for therapy
Bcl-2、浆细胞样 DC 和狼疮的轴作为治疗的基础
批准号:
nhmrc : GNT1105209
负责人:
Dr Yifan Zhan
金额:
$71.22万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --

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中文摘要
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英文摘要
Systemic lupus erythematosus (SLE) affects 1 in 1000 Australians, mostly women. Here the immune system goes awry and makes antibodies against the body’s own components including the body’s DNA. This leads to damage to many parts of the body including kidneys, joints, brain and heart. It is incurable. A particular immune cell controls the development of this disease and we have found this cell is selectively killed by an inexpensive drug, which we hope will be a better way of treating SLE.
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The axis of Bcl-2, plasmacytoid DCs and lupus as a basis for therapy
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