The development of store operated calcium channel monoclonal antibody inhibitors as a therapeutic option for breast cancer treatment

尽管乳腺癌的治疗最近取得了进展，但很大一部分患有这种疾病的妇女几乎没有从现有的治疗中受益，并死于乳腺癌。因此，需要新的治疗方法来治疗预后最差的乳腺癌。这项拨款利用了我们早期的发现，即一种特定的钙通道可能是乳腺癌的治疗靶点。这笔拨款将用于开发针对该靶点的抑制性单克隆抗体。

Despite recent advances in the treatment of breast cancer, a significant proportion of women with this disease receive little benefit from currently available treatments and die from breast cancer. Hence, new therapies for the breast cancers with the poorest prognosis are needed. This grant exploits our earlier finding that a specific calcium channel is a likely therapeutic target for breast cancer. Funding from this grant will be used to develop an inhibitory monoclonal antibody to this target.