The functional interplay between alpha synuclein and synaptophysin in synaptic vesicle recycling
The functional interplay between alpha synuclein and synaptophysin in synaptic vesicle recycling
批准号:
nhmrc : GNT1085483
负责人:
Dr Sarah Gordon
金额:
$39.14万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 --
中文摘要
帕金森病(PD)是第二大最常见的神经退行性疾病,影响着全球700万人。α-突触核蛋白是一种可能导致PD患者脑细胞死亡的脑内蛋白,但其正常作用尚不清楚。本研究将探讨α-突触核蛋白在维持正常健康脑活动中的作用。此外,这项工作将帮助我们了解神经退行性疾病状态(如PD)中出错的过程。
英文摘要
Parkinson’s Disease (PD) is the second most common neurodegenerative disorder, affecting 7 million people worldwide. α-synuclein is a protein in that brain that is likely to contribute to the death of brain cells in PD, but the normal role of the protein remains unknown. This study will investigate the function of α-synuclein in maintaining normal healthy brain activity. In addition, this work will help us understand the processes that go awry in neurodegenerative disease states such as PD.
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会议论文
Investigation of the molecular mechanisms underlying alpha synuclein function at the presynapse
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批准号:nhmrc : 1105478
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项目类别:Career Development Fellowships
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资助金额:$28.91万
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财政年份:2016
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负责人:Dr Sarah Gordon
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依托单位:
Investigation of the molecular mechanisms underlying alpha synuclein function at the presynapse
-
批准号:nhmrc : GNT1105478
-
项目类别:Career Development Fellowships
-
资助金额:$41.92万
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财政年份:2016
-
负责人:Dr Sarah Gordon
-
依托单位:
The functional interplay between alpha synuclein and synaptophysin in synaptic vesicle recycling
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批准号:nhmrc : 1085483
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项目类别:Project Grants
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资助金额:$27.04万
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财政年份:2015
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负责人:Dr Sarah Gordon
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依托单位:
海外基金