The impact of Pseudomonas aeruginosa biofilm on pathogenesis of microbial keratitis and the development of antimicrobial contact lenses for disease prevention

全世界有1.25亿人通过使用隐形眼镜矫正视力。隐形透镜的使用使佩戴者易患威胁视力的眼部感染。尽管有先进的材料技术和改善的卫生制度，但与接触镜有关的传染病的发病率仍然保持不变。这项研究旨在阐明细菌如何损害眼部免疫系统，以制定预防/治疗策略来对抗眼部感染。

Worldwide, 125 million people correct their vision through the use of contact lenses. Contact lens use predisposes the wearer to sight threatening eye infections. Despite advanced material technology and improved hygiene regimens, the rate of contact lens-related infectious disease has remained constant. This research aims to elucidate how bacteria compromise the ocular immune system in order to develop preventative/therapeutic strategies to combat ocular infections.