The Importance of Receptor Trafficking for Signalling of Pain and Inflammation

受体贩运对于疼痛和炎症信号传导的重要性

• 批准号: nhmrc : GNT1083054
• 负责人: Dr Meritxell Canals
• 金额: $ 75.39万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/importance-receptor-trafficking-pain-inflammation/1345484
• 关键词: Importance; Receptor; Trafficking; Signalling; Pain

Inflammation and pain are normal processes that are essential for survival: inflammation fights infections and pain allows avoidance of danger. These processes are normally tightly controlled and are transient. During disease, they become dysregulated and chronic. By understanding the normal processes of inflammation and pain, and by determining how dysregulation causes disease, we aim to develop new treatments for diseases that are a major cause of human suffering.

炎症和疼痛是生存所必需的正常过程：炎症对抗感染，疼痛可以避免危险。这些过程通常受到严格控制，并且是短暂的。在疾病期间，它们变得失调和慢性。通过了解炎症和疼痛的正常过程，并通过确定失调如何导致疾病，我们的目标是开发新的治疗方法，这些疾病是人类痛苦的主要原因。