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The influence of HIV on T cell function and application to vaccine design.

The influence of HIV on T cell function and application to vaccine design.
HIV 对 T 细胞功能的影响及其在疫苗设计中的应用。
批准号:
nhmrc : 1012178
负责人:
A/Pr Mina John
金额:
$28.53万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2014-12-31

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中文摘要
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英文摘要
Development of a safe, effective vaccine remains the only viable means of abating the human immunodeficiency virus (HIV) pandemic in the long term. Scientists must develop a vaccine that could protect against many diverse HIV strains worldwide. This research aims to understand the ways in which HIV mutates to avoid human immune responses in order to determine how best to design a vaccine. The findings could be applied to other infectious diseases for which vaccines are also needed.
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会议论文
Understanding pathogen effects on human T cell receptor diversity and function
  • 批准号:
    nhmrc : 1148284
  • 项目类别:
    Project Grants
  • 资助金额:
    $53.92万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Mina John
  • 依托单位:
Interactions between adaptable pathogens, drugs and the human host
  • 批准号:
    nhmrc : 384702
  • 项目类别:
    Programs
  • 资助金额:
    $381.9万
  • 财政年份:
    2006
  • 负责人:
    A/Pr Mina John
  • 依托单位:
Characterisation of polymorphism in HIV-1 sequence: investigation of viral escape from HLA-restricted immune responses
  • 批准号:
    nhmrc : 237412
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $28.36万
  • 财政年份:
    2003
  • 负责人:
    A/Pr Mina John
  • 依托单位:
the role of host MHC in HIV-1 sequence evolution, viral load and response to antiretroviral therapy
  • 批准号:
    nhmrc : 194811
  • 项目类别:
    NHMRC Postgraduate Scholarships
  • 资助金额:
    $3.75万
  • 财政年份:
    2002
  • 负责人:
    A/Pr Mina John
  • 依托单位:
国内基金
海外基金
人类免疫缺陷病毒(HIV)总核酸检测试剂盒
HIV相关肺癌免疫微环境中关键免疫细胞亚群的功能特征与调控机制研究
基于深度测序与SNV 芯片的HIV重复感染与毒株重组机制研究
  • 批准号:
    2026JJ81281
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2026
  • 负责人:
    徐艳
  • 依托单位:
PGT123中和抗体修饰的工程化载肽囊泡疫苗通过诱导CD4+ T细胞极化在抗HIV感染中的应用和机制研究