A DENDRITIC SUBSTRATE FOR THE CHOLINERGIC CONTROL OF NEOCORTICAL OUTPUT
A DENDRITIC SUBSTRATE FOR THE CHOLINERGIC CONTROL OF NEOCORTICAL OUTPUT
批准号:
nhmrc : 1144731
负责人:
Prof Elizabeth Coulson
金额:
$60.74万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2021-12-31
中文摘要
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英文摘要
The forebrain cholinergic system controls neocortical activity and cognitive function. This project will investigate the mechanisms by which the cholinergic system controls neocortical circuit activity in rodent models using advanced optical and electrical recording methods. The results will provide a foundation for the understanding of how dysfunction of the cholinergic system results in cognitive decline in humans, and identify new targets for improved treatment of human cognitive impairment.
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A DENDRITIC SUBSTRATE FOR THE CHOLINERGIC CONTROL OF NEOCORTICAL OUTPUT
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批准号:nhmrc : GNT1144731
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项目类别:Project Grants
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资助金额:$89.83万
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财政年份:2018
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负责人:Prof Elizabeth Coulson
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依托单位:
Regulation of neuronal cell death signalling for the treatment of neurodegenerative diseases
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批准号:LP110100403
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项目类别:Linkage Projects
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资助金额:$30.23万
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财政年份:2011
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负责人:Prof Elizabeth Coulson
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依托单位:
Molecular mechanisms of neuronal survival
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批准号:nhmrc : 569601
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项目类别:Career Development Fellowships
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资助金额:$28.58万
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财政年份:2009
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负责人:Prof Elizabeth Coulson
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依托单位:
A -induced cell death signalling by the p75 neurotrophin receptor.
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批准号:nhmrc : 569507
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项目类别:NHMRC Project Grants
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资助金额:$36.43万
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财政年份:2009
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负责人:Prof Elizabeth Coulson
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依托单位:
Regulation of p75 death signalling: How neurotransmitter- and neurotrophic- signals determine cell survival
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批准号:nhmrc : 511107
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项目类别:NHMRC Project Grants
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资助金额:$19.49万
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财政年份:2008
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负责人:Prof Elizabeth Coulson
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依托单位:
Proteolytic cleavage of the p75 neurotrophin receptor mediates cell death
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批准号:nhmrc : 301119
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项目类别:NHMRC Project Grants
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资助金额:$15.9万
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财政年份:2004
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负责人:Prof Elizabeth Coulson
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依托单位:
Molecular Mechanisms of Neuronal Cell Death in the Adult
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批准号:nhmrc : 301226
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项目类别:Career Development Fellowships
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资助金额:$29.64万
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财政年份:2004
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负责人:Prof Elizabeth Coulson
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依托单位:
海外基金