BRAIN-MEND: Biological Resource Analysis to Identify new mechanisms and phenotypes in Neurodegenerative Diseases
BRAIN-MEND: Biological Resource Analysis to Identify new mechanisms and phenotypes in Neurodegenerative Diseases
批准号:
nhmrc : GNT1151854
负责人:
A/Pr John Kwok
金额:
$85.0万
依托单位国家:
澳大利亚
项目类别:
Boosting Dementia Research Initiative
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --
中文摘要
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英文摘要
Current classification of neurodegenerative diseases (ND) based on clinical phenotypes does not take into account underlying disease heterogeneity, or overlapping disease mechanisms, thus hindering therapy development. Segregation and re-classification of ND phenotypes is urgently needed. BRAIN-MEND will reclassify existing phenotypic classifications using using pathway and network analyses within and across complex NDs.
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会议论文
The role of mutant CYLD in frontotemporal dementia and motor neuron disease
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批准号:nhmrc : GNT1140708
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项目类别:Project Grants
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依托单位:
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批准号:nhmrc : GNT1095127
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财政年份:2015
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负责人:A/Pr John Kwok
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依托单位:
Non-Alzheimer’s disease degenerative dementias: Identifying prodromal genetic/familial phenotypes, modifying factors, and protein variations involved in progression
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批准号:nhmrc : 1095127
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财政年份:2015
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负责人:A/Pr John Kwok
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依托单位:
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批准号:nhmrc : GNT1062539
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项目类别:Project Grants
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财政年份:2014
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依托单位:
Mutations in ubiquitin proteasome pathway genes as a cause of frontotemporal dementia and motor neuron disease
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批准号:nhmrc : 1062539
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项目类别:Project Grants
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依托单位:
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批准号:nhmrc : 1021269
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财政年份:2012
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依托单位:
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批准号:nhmrc : 510218
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资助金额:$38.93万
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财政年份:2008
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依托单位:
Biological Characterisation of the Opiod Receptor Sigma 1 Gene in the Frontotemporal Dementia and Motor Neuron Disease
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批准号:nhmrc : 510217
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资助金额:$32.02万
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财政年份:2008
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负责人:A/Pr John Kwok
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依托单位:
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批准号:nhmrc : 276401
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资助金额:$27.56万
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财政年份:2004
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负责人:A/Pr John Kwok
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依托单位:
Alzheimer's disease and Dementia with Lewy bodies: How different are they?
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批准号:nhmrc : 300400
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项目类别:NHMRC Project Grants
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资助金额:$37.71万
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财政年份:2004
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负责人:A/Pr John Kwok
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依托单位:
Identification and Characterisation of Causative and Modifier Genes Involved in Variant Forms of Alzheimer's Disease
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负责人:A/Pr John Kwok
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依托单位:
海外基金