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Biological Characterisation of the Opiod Receptor Sigma 1 Gene in the Frontotemporal Dementia and Motor Neuron Disease

Biological Characterisation of the Opiod Receptor Sigma 1 Gene in the Frontotemporal Dementia and Motor Neuron Disease
额颞叶痴呆和运动神经元疾病中阿片受体 Sigma 1 基因的生物学特征
批准号:
nhmrc : 510217
负责人:
A/Pr John Kwok
金额:
$32.02万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2010-12-31

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中文摘要
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英文摘要
Frontotemporal dementia (FTD) and motor neuron disease (MND) are the two common causes of dementia and neurodegeneration. We have identified a new genes that causes familial FTD and MND in pedigrees affected with dementia and-or MND.This project will study the expression and function of this new FTD-MND gene to determine its role in the aetiology and pathology of this complex of neurodegenerative disorders.
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会议论文
BRAIN-MEND: Biological Resource Analysis to Identify new mechanisms and phenotypes in Neurodegenerative Diseases
  • 批准号:
    nhmrc : GNT1151854
  • 项目类别:
    Boosting Dementia Research Initiative
  • 资助金额:
    $85.0万
  • 财政年份:
    2018
  • 负责人:
    A/Pr John Kwok
  • 依托单位:
The role of mutant CYLD in frontotemporal dementia and motor neuron disease
  • 批准号:
    nhmrc : GNT1140708
  • 项目类别:
    Project Grants
  • 资助金额:
    $96.32万
  • 财政年份:
    2018
  • 负责人:
    A/Pr John Kwok
  • 依托单位:
Non-Alzheimer’s disease degenerative dementias: Identifying prodromal genetic/familial phenotypes, modifying factors, and protein variations involved in progression
  • 批准号:
    nhmrc : GNT1095127
  • 项目类别:
    Boosting Dementia Research Initiative
  • 资助金额:
    $644.92万
  • 财政年份:
    2015
  • 负责人:
    A/Pr John Kwok
  • 依托单位:
Non-Alzheimer’s disease degenerative dementias: Identifying prodromal genetic/familial phenotypes, modifying factors, and protein variations involved in progression
  • 批准号:
    nhmrc : 1095127
  • 项目类别:
    Targeted Calls
  • 资助金额:
    $451.3万
  • 财政年份:
    2015
  • 负责人:
    A/Pr John Kwok
  • 依托单位:
海外基金