Cell Survival Pathways as Potential Targets in Breast Cancer
Cell Survival Pathways as Potential Targets in Breast Cancer
细胞生存途径作为乳腺癌的潜在靶点
批准号：
nhmrc : GNT1094320
负责人：
Dr James Whittle
金额：
$12.07万
依托单位国家：
澳大利亚
项目类别：
Postgraduate Scholarships
财政年份：
2015
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2015-01-01 至 --
中文摘要
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英文摘要
Cancer cells are characterised by their capacity for relentless growth, survival and evasion of cell death. This proposal will use patient derived xenograft models of primary breast cancer to test the hypothesis that addition of BH3-mimetics could improve response to anti-HER2 therapy. This technique involves transplantation of patient tumours into immune-compromised mice. This represents a useful method for testing new agents.
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