Cell therapy for enteric neuropathies - the essential next steps

由于缺乏有效的治疗方法，由肠壁神经元损伤或病变引起的胃肠运动障碍（肠性神经病）是临床上最具挑战性的疾病之一。我们最近的动物研究表明，以细胞为基础的疗法是治疗肠道神经病的一种真正的可能性。在这个项目中，我们将有条不紊地解决需要解决的突出步骤，目的是将肠细胞疗法推向临床。

Gastrointestinal motility disorders caused by damage or diseased neurons in the gut wall ('enteric neuropathies) are some of the most clinically challenging conditions to manage because of a lack of effective treatments. Our recent animal studies suggest that cell-based therapies are a real possibility to treat enteric neuropathies. In this project, we will methodically address the outstanding steps that need to be addressed with the aim of moving enteric cell therapies to the clinic.