Cell therapy for the prevention and treatment of invasive filamentous fungal infections in patients with haematological malignancies

细胞疗法预防和治疗血液恶性肿瘤患者侵袭性丝状真菌感染

• 批准号: nhmrc : 1029467
• 负责人: Prof David Gottlieb
• 金额: $ 65.87万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cell-therapy-prevention-haematological-malignancies/110688
• 关键词: Cell; therapy; prevention; treatment; invasive

Common fungi in the environment do not cause disease in healthy individuals. They are however responsible for fatal infections leading to death when the immune system is impaired following treatment for blood cancers. This project aims to restore defects in the immune system of these patients by giving them cells that have been grown to recognize and kill fungus.

环境中常见的真菌不会引起健康个体的疾病。然而，当血癌治疗后免疫系统受损时，它们会导致致命的感染，导致死亡。该项目旨在通过给予这些患者已经生长的细胞来识别和杀死真菌，从而恢复这些患者免疫系统的缺陷。