Establishment of a bank of third party T cells to treat virus infections (that are resistant or unsuitable for other forms of antibiotic therapy) in immunocompromised and transplant patients across Australia

建立第三方 T 细胞库，用于治疗澳大利亚各地免疫功能低下和移植患者的病毒感染（对其他形式的抗生素治疗具有耐药性或不适合其他形式的抗生素治疗）

• 批准号: nhmrc : 1032431
• 负责人: Prof David Gottlieb
• 金额: $ 54.11万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/establishment-bank-party-patients-australia/110848
• 关键词: Establishment; bank; third; party; cells

Bone marrow transplantation can cure cancers of the blood but patients are susceptible to viral infections due to ongoing immune deficiency. We have shown you can grow immune cells in the laboratory and transfer this immunity to transplant recipients. While effective, this has not been widely adopted due to the time, complexity and costs of the process. We aim to address these issues by providing a treatment option for patients with life threatening infections using immediately available “off the shelf” immune cells.

骨髓移植可以治愈血癌，但由于持续的免疫缺陷，患者容易受到病毒感染。我们已经证明了你可以在实验室培养免疫细胞并将这种免疫转移到移植接受者身上。虽然有效，但由于时间、复杂性和成本的原因，这种方法尚未被广泛采用。我们的目标是通过使用立即可用的“现成”免疫细胞为危及生命的感染患者提供治疗选择来解决这些问题。