Cellular Mechanisms Underlying Neurodegenerative disease and the neuronal response to trauma

神经退行性疾病的细胞机制和神经元对创伤的反应

• 批准号: nhmrc : 490047
• 负责人: Prof Tracey Dickson
• 金额: $ 27.09万
• 依托单位: Antarctic Climate and Ecosystems CRC, University of Tasmania
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cellular-mechanisms-underlying-response-trauma/115428
• 关键词: Cellular; Mechanisms; Underlying; Neurodegenerative; disease

Brain and spinal cord injury are major causes of death and disability, with degenerative diseases similarly affecting large proportions of the population. The singular objective of my research proposal is to increase our understanding of the molecular and cellular processes by which nerve cells respond to trauma and diseases such as Alzheimer’s and Parkinson’s, and to identify new therapeutic approaches aimed at encouraging the repair of damaged cells.

脑和脊髓损伤是造成死亡和残疾的主要原因，退行性疾病同样影响很大一部分人口。我的研究计划的唯一目标是增加我们对神经细胞对创伤和疾病（如阿尔茨海默氏症和帕金森症）的反应的分子和细胞过程的理解，并确定旨在促进受损细胞修复的新治疗方法。