Microtubule stabilisation: promoting adaptive plasticity, brain healing and functional recovery after traumatic brain injury

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Traumatic brain injury (TBI) continues to be the leading cause of death and disability for individuals under 45 years of age. There are currently no effective pharmacotherapeutics available that are able to prevent or minimise brain damage following TBI. My team will use sophisticated in vivo techniques to fully characterise the brain's response to injury and to test whether microtubule stabilisation via new generation taxol-like drugs improves post-trauma outcomes.