mRNA surveillance in human disease: Molecular determinants of nonsense-mediated mRNA decay

人类疾病中的 mRNA 监测：无义介导的 mRNA 衰变的分子决定因素

• 批准号: nhmrc : 400131
• 负责人: Prof John Bateman
• 金额: $ 31.64万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mrna-surveillance-human-mrna-decay/77014
• 关键词: mRNA; surveillance; human; disease; Molecular

Inherited diseases are a common cause of human disability, illness and suffering. It has been estimated that 5-10% of the population will be affected by disorders with a genetic component. Thus studies on mechanisms of inherited diseases, especially those

遗传性疾病是导致人类残疾、疾病和痛苦的常见原因。据估计，5%-10%的人口将受到带有遗传成分的疾病的影响。因此，遗传性疾病的发病机制研究，特别是那些