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Regulation of astrocytic gliosis and axonal regeneration in EAE by EphA4

Regulation of astrocytic gliosis and axonal regeneration in EAE by EphA4
EphA4 对 EAE 中星形胶质细胞增生和轴突再生的调节
批准号:
nhmrc : 566513
负责人:
A/Pr Ann Turnley
金额:
$35.5万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2011-12-31

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中文摘要
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英文摘要
Multiple Sclerosis (MS) is a debilitating disease with currently no effective cure. Apart from losing the protective insulating sheath called myelin, nerve cells are damaged and a scar forms. If this could be prevented then MS may be better treated. Using a model of MS called EAE, the role of a molecule, EphA4, will be examined for its ability to induce nerve loss and scar formation and to determine whether blocking it will promote repair, leading to a therapy for MS.
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