Replacement therapies for improving outcome following preterm birth

早产是一个日益严重的重大健康问题，可导致晚年严重的行为和认知障碍。即使是中度早产的儿童，患这些疾病的风险也会增加。我们认为胎盘中促进生长的类固醇激素的过早丧失会导致次优发育。该项目将检查在早产新生儿中更换这些激素以改善儿童预后的有效性。

Premature birth is a major and growing health problem and can lead to serious behavioural and cognitive disorders in later life. Even moderately prematurely born children are at increased risk of developing these disorders. We propose that premature loss of support from growth promoting steroid hormones from the placenta lead to suboptimal development. This project will examine the effectiveness of replacing these hormones in prematurely born neonates for improving outcomes in childhood.