Replacement therapies for improving outcome following preterm birth

改善早产后结局的替代疗法

• 批准号: nhmrc : GNT1161981
• 金额: $ 89.2万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/replacement-therapies-improving-preterm-birth/1379200
• 关键词: Replacement; therapies; improving; outcome; following

Premature birth is a major and growing health problem and can lead to serious behavioural and cognitive disorders in later life. Even moderately prematurely born children are at increased risk of developing these disorders. We propose that premature loss of support from growth promoting steroid hormones from the placenta lead to suboptimal development. This project will examine the effectiveness of replacing these hormones in prematurely born neonates for improving outcomes in childhood.

早产是一个日益严重的重大健康问题，可能导致晚年严重的行为和认知障碍。即使是中度早产的儿童也有增加患这些疾病的风险。我们认为，过早失去来自胎盘的促生长类固醇激素的支持，导致发育不佳。该项目将研究在早产新生儿中替代这些激素以改善儿童结局的有效性。