The role of angiotensin converting enzyme 2 in diabetic complications

血管紧张素转换酶2在糖尿病并发症中的作用

• 批准号: nhmrc : 526642
• 负责人: Dr Christos Tikellis
• 金额: $ 30.22万
• 依托单位: Baker IDI Heart and Diabetes Institute
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-angiotensin-converting-diabetic-complications/94451
• 关键词: role; angiotensin; converting; enzyme; diabetic

Most heart attacks and strokes arise from narrowing of the arteries. This process is regulated by a number of hormonal pathways. One of the most important is the renin angiotensin system. Our group has demonstrated important changes in this pathway which play a pivotal role in regulating the development of atherosclerosis and its response to treatment. It is predicted that these studies will provide critical information to develop innovative treatment strategies for cardiovascular disease.

大多数心脏病发作和中风都是由动脉狭窄引起的。这一过程受许多激素途径的调节。其中最重要的是肾素血管紧张素系统。我们的小组已经证明了这一途径的重要变化，在调节动脉粥样硬化的发展及其对治疗的反应中起着关键作用。预计这些研究将为开发心血管疾病的创新治疗策略提供关键信息。