Role of BIME1 in breast cancer

BIME1 在乳腺癌中的作用

• 批准号: nhmrc : GNT1104887
• 负责人: A/Pr Andreas Moeller
• 金额: $ 46.86万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-bime1-breast-cancer/1346397
• 关键词: Role; BIME1; breast; cancer

We have identified genetic abnormalities in 5% of breast cancers that fall in a novel DNA element called BIME1. This proposal aims to determine whether these genetic abnormalities contribute to breast tumourigenesis and which genes and pathways are affected by these mutations. The outcomes of this proposal may lead to the development of novel therapies for breast cancer or could influence the choice of existing therapies for patients that harbour these genetic abnormalities.

我们已经在5%的乳腺癌中发现了一种名为BIME1的新型DNA元素的遗传异常。这一建议旨在确定这些基因异常是否有助于乳腺肿瘤的发生，以及哪些基因和途径受到这些突变的影响。这一建议的结果可能会导致乳腺癌新疗法的发展，或者可能影响对携带这些基因异常的患者的现有疗法的选择。