Exosomes as mediators of metastasis

肿瘤分泌因子，这些因子包含在称为外泌体的特殊结构中，用于为随后进入的肿瘤细胞准备身体的其他器官，从而促进癌症的致命扩散。该项目将研究外泌体在肿瘤细胞到达之前改变器官的方式，肺癌患者中这些外泌体的组成，以及它们是否是疾病进展和治疗干预的新标志物。

Tumours secrete factors which are contained in specific structures called exosomes, and are used to prepare other organs of the body for subsequently incoming tumour cells, thereby facilitating the often mortal spread of the cancer. This project will investigate the way exosomes alter organs before tumour cells arrive, the composition of these exosomes in lung cancer patients and if they are novel markers for diseases progression as well as therapeutic intervention.