Sympathetic Nervous System Regulation of the Tumour Microenvironment

转移是乳腺癌发病率和死亡率的主要原因。这些研究将评估将交感神经系统作为癌症进展途径的常见调节系统的翻译机会。通过利用敏感的成像技术对应激生物学进行非侵入性、实时的评估，这些研究将确定在肿瘤微环境中工作的神经内分泌机制，以支持癌细胞在靶器官中的扩散和阻止。

Metastasis is the major cause of morbidity and mortality in breast cancer. These studies will evaluate the translational opportunity of targeting the sympathetic nervous system as a common regulator of cancer progression pathways. By exploiting sensitive imaging technology for non-invasive, real-time assessment of stress biology, these studies will define the neuroendocrine mechanisms that operate in the tumour microenvironment to support dissemination and arrest of cancer cells in target organs.