The role of the clotting cascade in aortic aneurysm and associated cardiovascular events

凝血级联在主动脉瘤和相关心血管事件中的作用

• 批准号: nhmrc : 1003707
• 负责人: A/Pr Catherine Rush
• 金额: $ 43.42万
• 依托单位: James Cook University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-clotting-cascade-cardiovascular-events/108961
• 关键词: role; clotting; cascade; aortic; aneurysm

Weakening of the main abdominal artery is responsible for approximately 1000 deaths/ year in Australia. Most weakened arteries are identified at an early stage but there is no current therapy which limits the progression of artery weakening. There is also no model which predicts the complications associated with weakened arteries. In the current project we propose the importance of clot in progression and complications of weakened arteries. We will undertake studies to identify new therapies and a predictive model for weakened arteries.

在澳大利亚，主要腹部动脉的弱化每年导致约1000例死亡。大多数弱化的动脉在早期阶段被识别，但目前没有限制动脉弱化进展的治疗方法。也没有模型可以预测与动脉变弱相关的并发症。在目前的项目中，我们提出了血栓在动脉衰弱的进展和并发症中的重要性。我们将开展研究，以确定新的治疗方法和动脉衰弱的预测模型。