The role of glutathione transferase P1 in regulating allergic airways disease

谷胱甘肽转移酶 P1 在调节过敏性气道疾病中的作用

• 批准号: nhmrc : 471401
• 负责人: Dr Dianne Webb
• 金额: $ 29.13万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-glutathione-transferase-airways-disease/94539
• 关键词: role; glutathione; transferase; P1; regulating

Recent studies have shown that a single amino acid change in an enzyme called glutathione tranferase Pi (GSTP)1 protects against the likelihood of developing asthma. This enzyme is found in the cells that line the airways and detoxifies harmful chemicals such as those found in pollutants and cigarette smoke. The aim of our study is to understand how GSTP1 protects against the development of asthma.

最近的研究表明，一种叫做谷胱甘肽转移酶Pi（GSTP）1的酶中的一个氨基酸变化可以预防哮喘的发生。这种酶存在于气道细胞中，可以消除有害化学物质，如污染物和香烟烟雾中的有害化学物质。我们研究的目的是了解GST 1如何预防哮喘的发展。