The role of Interferon-regulatory Factors in the host defense against bacterial infection

干扰素调节因子在宿主防御细菌感染中的作用

• 批准号: nhmrc : GNT1091544
• 负责人: Dr Si Ming Man
• 金额: $ 33.43万
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-interferon-regulatory-bacterial-infection/1345842
• 关键词: role; Interferon; regulatory; Factors; host

Type I interferons are used in the treatment of viral infection. However, the therapeutic potential of type I interferons for the treatment of bacterial infection is not known because we do not fully understand their functional roles and regulation in hosts infected with bacteria. My proposal aims to investigate the role of one family of regulatory proteins, known as interferon-regulatory factors, in the host defense against foodborne bacteria.

I型干扰素用于治疗病毒感染。然而，I型干扰素治疗细菌感染的潜力尚不清楚，因为我们不完全了解它们在细菌感染宿主中的功能作用和调节。我的建议旨在研究一个调节蛋白家族的作用，被称为干扰素调节因子，在宿主防御食源性细菌。