Molecular mechanisms of inflammasome activation

炎症小体激活的分子机制

• 批准号: nhmrc : GNT1162025
• 负责人: Dr Si Ming Man
• 金额: $ 43.7万
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/molecular-mechanisms-inflammasome-activation/1349355
• 关键词: Molecular; mechanisms; inflammasome; activation

Infectious diseases are a leading cause of deaths in Australia. Disease-fighting proteins generated from a cell can trigger the killing of invading microorganisms, such as bacteria and viruses. In this CDF1 application, I will explore the possibility of harnessing the activity of these killer proteins to enhance immunity to deadly bacterial infections. Understanding how these anti-microbial proteins work could reveal new ways to fight infectious diseases.

在澳大利亚，传染病是导致死亡的主要原因。从细胞中产生的抗病蛋白质可以杀死入侵的微生物，如细菌和病毒。在这个CDF1应用中，我将探索利用这些杀手蛋白的活性来增强对致命细菌感染的免疫力的可能性。了解这些抗微生物蛋白的工作原理可以揭示对抗传染病的新方法。