Role of microRNA-21 in diabetic kidney disease

microRNA-21在糖尿病肾病中的作用

• 批准号: nhmrc : 1060448
• 负责人: Dr Phillip Kantharidis
• 金额: $ 50.31万
• 依托单位: Baker IDI Heart and Diabetes Institute
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-microrna-21-kidney-disease/454823
• 关键词: Role; microRNA; 21; diabetic; kidney

In various kidney diseases including the most common cause of end stage kidney disease, diabetic nephropathy, identifying the molecular mechanisms responsible for kidney failure will greatly assist in defining new therapeutic targets in order to develop new treatments and therapies. The studies described in this proposal highlight the involvement of a novel class of small RNA molecules, and provide us with a novel approach to tackle this disease.

在各种肾脏疾病中，包括终末期肾脏疾病的最常见原因糖尿病肾病，确定导致肾衰竭的分子机制将极大地有助于定义新的治疗靶点，以便开发新的治疗和疗法。该提案中描述的研究强调了一类新型小RNA分子的参与，并为我们提供了一种新的方法来解决这种疾病。