Role of a PI3K regulator in breast cancer.

PI3K 调节剂在乳腺癌中的作用。

• 批准号: nhmrc : 1061344
• 负责人: Dr Lisa Ooms
• 金额: $ 39.73万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-pi3k-regulator-breast-cancer/454886
• 关键词: Role; PI3K; regulator; breast; cancer.

Breast cancer is the most common malignancy among females which affects 1 in 8 women. Normal cells only divide when they receive a stimulus however cancer cells divide uncontrollably and are able to spread to other sites in the body, a process known as metastasis. We have identified a cancer suppressing gene which regulates cancer spread. This grant aims to characterise the mechanisms by which this gene controls cell movement and breast cancer spread.

乳腺癌是女性中最常见的恶性肿瘤，每8名女性中就有1名患有乳腺癌。正常细胞只有在接受刺激时才分裂，而癌细胞则无法控制地分裂，并能够扩散到身体的其他部位，这一过程称为转移。我们已经确定了一种控制癌症扩散的抑癌基因。该基金旨在研究该基因控制细胞运动和乳腺癌扩散的机制。