Characterisation of PI3-kinase-dependent signalling networks in breast cancer

乳腺癌中 PI3 激酶依赖性信号网络的表征

• 批准号: nhmrc : 1121472
• 负责人: Dr Lisa Ooms
• 金额: $ 62.48万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/characterisation-pi3-kinase-breast-cancer/946735
• 关键词: Characterisation; PI3; kinase; dependent; signalling

Breast cancer affects 1 in 8 women in Australia. Cancer cells are able to spread to other sites in the body by a process known as metastasis which is the leading cause of breast cancer death. We have identified a gene which controls breast cancer growth and metastasis. This grant aims to elucidate the mechanisms by which this gene co-operates with another gene to regulate breast cancer growth and metastasis which thereby may affect disease outcome.

乳腺癌影响澳大利亚八分之一的女性。癌细胞能够通过称为转移的过程扩散到身体的其他部位，这是乳腺癌死亡的主要原因。我们已经确定了一个控制乳腺癌生长和转移的基因。该基金旨在阐明该基因与另一个基因合作调节乳腺癌生长和转移的机制，从而可能影响疾病的结果。