The role of sodium channels in pain and cold allodynia

钠通道在疼痛和冷异常性疼痛中的作用

• 批准号: nhmrc : 1045592
• 负责人: Dr Irina Vetter
• 金额: $ 23.29万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-sodium-channels-cold-allodynia/111769
• 关键词: role; sodium; channels; pain; cold

Many types of chronic pain remain poorly treated and severely impact the quality of life of millions of Australians. Cold allodynia in particular, which occurs in several painful human conditions and leads to severe pain from simply touching a cool surface or item, is poorly understood and thus difficult to treat. The aim of this project is to determine the pharmacological mechanism of cold allodynia to develop novel treatment approaches.

许多类型的慢性疼痛仍然得不到治疗，严重影响了数百万澳大利亚人的生活质量。特别是寒冷的异常性痛症，它发生在几种痛苦的人类状况下，仅仅接触凉爽的表面或物品就会导致严重的疼痛，人们对它知之甚少，因此难以治疗。本项目的目的是确定感冒异常性痛的药理学机制，以开发新的治疗方法。