The role of subgenomic non-coding viral RNA in flavivirus pathogenicity

亚基因组非编码病毒RNA在黄病毒致病性中的作用

• 批准号: nhmrc : 631365
• 负责人: Dr Anneke Funk
• 金额: $ 37.03万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-subgenomic-non-flavivirus-pathogenicity/98449
• 关键词: role; subgenomic; non; coding; viral

Flaviviruses are transmitted by insects and pose a serious health threat to the Australian population. They can cause fever syndromes, encephalitis and death. We aim at better understanding of how these viruses cause disease. We are particularly interested in elucidating the role of small non-coding nucleic acid produced by flaviviruses in the viral pathogenicity. Ultimately, this deeper understanding should lead to the development of effective vaccines and antiviral therapies.

黄病毒通过昆虫传播，对澳大利亚人的健康构成严重威胁。它们会导致发烧症状、脑炎和死亡。我们的目标是更好地了解这些病毒是如何导致疾病的。我们特别感兴趣的是阐明由黄病毒产生的非编码小核酸在病毒致病中的作用。最终，这种更深入的理解应该会导致有效疫苗和抗病毒疗法的开发。