The role of noncoding subgenomic flavivirus RNA in virus-host interactions
The role of noncoding subgenomic flavivirus RNA in virus-host interactions
批准号:
nhmrc : 1045080
负责人:
Prof Alexander Khromykh
金额:
$41.64万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2015-12-31
中文摘要
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英文摘要
Flaviviruses such as Dengue, Japanese encephalitis , and West Nile are major human pathogens causing more than 50 million infections per year. Elements in viral genome responsible for pathogenesis of these viruses are not well defined. Recently we have identified a unique for these viruses noncoding subgenomic flavivirus RNA (sfRNA) and showed that it is contributing to viral pathogenesis. In this proposal we aim to determine mechanisms by which sfRNA facilitates viral pathogenesis.
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国内基金
海外基金
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