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The role of thymocyte self-renewal in causing T cell leukaemia

The role of thymocyte self-renewal in causing T cell leukaemia
胸腺细胞自我更新在引起T细胞白血病中的作用
批准号:
nhmrc : 628368
负责人:
A/Pr David Curtis
金额:
$39.11万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31

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中文摘要
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英文摘要
Recurrence of acute leukamia after therapy is due to the presence of immature cells that can self-renew, a process that is normally restricted to stem cells. Through the study of mice that develop leukaemia, we have identified these very rare self-renewing cells that are resistant to standard therapies. We can identify and measure these cells many months before leukaemia develops. As such, we will use this mouse model to understand how these cells self-renew and how they can be killed
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Curing blood cancers: rapid translation from target to drug to clinic
  • 批准号:
    nhmrc : 1139466
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $47.83万
  • 财政年份:
    2018
  • 负责人:
    A/Pr David Curtis
  • 依托单位:
Curing blood cancers: rapid translation from target to drug to clinic
  • 批准号:
    nhmrc : GNT1139466
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $64.02万
  • 财政年份:
    2018
  • 负责人:
    A/Pr David Curtis
  • 依托单位:
Centre for Blood Transplant and Cell Therapy
  • 批准号:
    nhmrc : GNT1135107
  • 项目类别:
    Centres of Research Excellence
  • 资助金额:
    $250.0万
  • 财政年份:
    2017
  • 负责人:
    A/Pr David Curtis
  • 依托单位:
Centre for Blood Transplant and Cell Therapy
  • 批准号:
    nhmrc : 1135107
  • 项目类别:
    Centres of Research Excellence
  • 资助金额:
    $168.96万
  • 财政年份:
    2017
  • 负责人:
    A/Pr David Curtis
  • 依托单位:
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