Characterization of appetite-regulating peptides in fish

在脊椎动物中，复杂的激素网络调节着摄食、能量平衡和生长。下丘脑因子如神经肽Y （NPY）、食欲素和可卡因和安非他明调节转录物（CART）最终通过刺激或减少食欲来控制这些功能。其他激素，特别是胃肠道激素，如胰淀素和胆囊收缩素，在循环中释放并到达大脑，在那里它们可以调节这些中心因素的作用。环境因素（如温度）也可能影响进食和食欲相关因素。此外，鉴于能量储备与繁殖之间的联系，这些中央摄食调节因子也可能受到繁殖事件的影响，是重要的繁殖调节因子。

In vertebrates, complex hormonal networks regulate feeding, energy homeostasis and growth. Hypothalamic factors such as neuropeptide Y (NPY), orexins and cocaine and amphetamine regulated transcript (CART) ultimately control these functions by either stimulating or decreasing appetite. Other hormones, in particular gastrointestinal hormones such as amylin and cholecystokinin are released in the circulation and reach the brain where they can modulate the actions of these central factors. Environmental factors (e.g. temperature) might also affect feeding and appetite-related factors. In addition, given the link between energy reserves and reproduction, these central feeding regulators might also be influenced by reproductive events and be important regulators of reproduction.