Sialyltransferase in the bipolar and schizophrenic brain: examining the role of a novel generalised susceptibility gene

双相情感障碍和精神分裂症大脑中的唾液酸转移酶：检查新型广义易感基因的作用

• 批准号: nhmrc : 630574
• 负责人: A/Pr Jennifer Donald
• 金额: $ 34.18万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/sialyltransferase-bipolar-schizophrenic-susceptibility-gene/77108
• 关键词: Sialyltransferase; bipolar; schizophrenic; brain; examining

Bipolar disorder and schizophrenia are two major psychiatric conditions affecting over 800,000 Australians. We have identified a new gene which contributes to increased risk to developing both bipolar disorder and schizophrenia. We will investigate the function of this gene in normal brain development, and how this function is disrupted in individuals with bipolar disorder and schizophrenia. Understanding the biological cause will help us define better treatments for these severe mental illnesses.

双相情感障碍和精神分裂症是影响80多万澳大利亚人的两种主要精神疾病。我们已经发现了一种新的基因，它会增加患双相情感障碍和精神分裂症的风险。我们将研究该基因在正常大脑发育中的功能，以及这种功能在双相情感障碍和精神分裂症患者中是如何被破坏的。了解生物学原因将有助于我们为这些严重的精神疾病找到更好的治疗方法。