Strategies to enhance CD4 T cell-mediated anti-tumour immunity
Strategies to enhance CD4 T cell-mediated anti-tumour immunity
批准号:
nhmrc : 1012930
负责人:
Dr Elena Shklovskaya
金额:
$35.31万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2014-12-31
中文摘要
免疫系统能够控制癌症,但通常不能做到这一点。在这个项目中,我们将研究两个影响抗癌免疫反应的因素:抑制免疫反应的调节性T细胞和破坏对肿瘤的潜在有益反应的耐受性树突状细胞。通过操控这些因素,我们希望提高抗癌免疫反应的有效性。
英文摘要
The immune system is capable of controlling cancer, but frequently does not do so. In this project we will study two factors that compromise anti-cancer immune responses: regulatory T cells, which suppress immune responses, and tolerogenic dendritic cells, which subvert potentially beneficial responses to tumours. By manipulating these factors, we hope to enhance the effectiveness of the immune response against cancer.
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会议论文
Role of dendritic cell subsets in the generation of CD4 T cell memory
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批准号:nhmrc : 570772
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项目类别:NHMRC Project Grants
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资助金额:$37.58万
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财政年份:2009
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负责人:Dr Elena Shklovskaya
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依托单位:
海外基金